Lecturer

Prof. Dr. Margarita Calvo
Associate Professor, Faculty of Biological Sciences and Medical School
Pontificia Universidad Católica de Chile, Santiago, Chile

The lecture will be held in English. 

All CRU 5001 members and colleagues from UKW are warmly invited.

The responsible project members will present each project and first results

Project 6 investigates the mechanisms of presynaptic plasticity and the reorganization of nociceptive terminals in the skin. An established mouse skin-nerve preparation and genetically modified Drosophila models are used to analyze the role of specific genes and signaling pathways in pain processing. The aim is to better understand how peripheral stimuli contribute to the persistence of chronic pain.

Further information on Project 6

Project 7 focuses on the role of the blood-brain and blood-nerve barriers in chronic pain. The project examines the reversible opening of these barriers after nerve injury and its relevance for central sensitization and pain chronification, particularly in complex regional pain syndrome (CRPS).

Further information on Project 7

The responsible project members will present the new project and first results.

Project 4 investigates cortical and subcortical networks that modulate nociceptive signals via top-down influences on the brainstem. The goal is to identify key neural circuits involved in chronic pain. The project uses advanced imaging and electrophysiological techniques in mouse models, complemented by translational approaches.

Further information on Project 4

Selection Symposium for KFO-(Advanced) Clinician Scientists of the second funding period 

Candidates will present their proposed projects covering diverse aspects of translational pain research. Following the presentations, closed-door interviews with the review panel will be held. The symposium aims to identify and select new (Advanced) Clinician Scientists for the structured support program within KFO 5001.

Lecturer

Prof. Dr. Allan Basbaum
Chair, Department of Anatomy
University of California, San Francisco (UCSF), United States

The lecture will be held in English. 

All CRU 5001 members and colleagues from UKW are warmly invited.

The responsible project members will present each project and first results

Project 8 investigates how nerve growth factor-induced axonal signaling, especially via interleukin-7, contributes to the development and resolution of chronic postoperative pain after abdominal hernia surgery. The aim is to identify mechanisms that could be targeted to improve postsurgical pain management.

Further information on Project 8

Project 9 explores how specific subtypes of local macrophages and satellite glial cells (SGCs) are involved in the natural resolution of pain following nerve injury. Using animal models and patient samples, the project seeks to better understand cellular healing processes and immune-glia interactions.

Further information on Project 9